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Exercise may help stay younger by growing new blood vessels

Amy Peck - Expert Contributor
Contributed by Amy Peck Expert Contributor
Teddy Gordon - Editor-in-Chief
Written by Teddy Gordon Editor-in-Chief
Fact checked
Training 2 min read
Updated: Dec 03, 2025
Fact checked

Key Findings

  • Exercise can promote angiogenesis (growth of new blood vessels), and lymphangiogenesis (growth of new lymph vessels), which often decline with age;
  • These vascular change can improve the immune system, tissue repair in many organs, waste detoxification, and the transportation of nutrients and oxygen;
  • Exercise-induced vessel growth is a promising natural anti-aging strategy, but ideal exercise regimens are still unknown.

New research shows that regular exercise may slow down aging and make you healthier by making your body grow new blood and lymphatic vessels.

Researchers at a Chinese medical institute published a review related to findings that physical activity stimulates two important processes: angiogenesis (the production of new blood vessels) and lymphangiogenesis (the creation of new lymphatic vessels).

Why It Matters

These functions are very important for keeping the immune system healthy, getting rid of waste, and giving tissues oxygen and nutrients. They often get worse as people get older.[1] 

Exercise is a strong, natural signal that starts both angiogenesis and lymphangiogenesis, which are processes that help keep our blood vessels healthy and our immune system working as we get older.

― says the lead researcher

For example, it increases the production of growth factors. This also helps the body repair faster, keeps the metabolism in balance, and improves the immune system. This may help keep important organs including the heart, muscles, brain, and skin healthy.

The study claims that exercise promotes biological processes that help form and change blood vessels. [2]

Better blood flow in the heart and blood vessels can lower the risk of heart disease and help all the organs work better. In skeletal muscle, better blood flow can help sustain strength and reduce muscular atrophy. Exercise-induced vascular growth in the brain may improve cognitive function and provides protection against neurodegenerative diseases.

Metric Value Notes
Duration of rat treadmill exercise 16 weeks Left-ventricle improvements after ischemia–reperfusion observed in aged rats (20–24 months)
Duration of mixed aerobic + resistance training in aged rats 8 weeks Resulted in significantly enhanced cardiac tissue angiogenesis (20–24-month-old rats)
Age of “old” mice in cardiac lymphatic remodeling study 20 months Compared to 2-month-old young mice
Study factsheet.

What to Keep in Mind

The researchers indicate that there are still a lot of unanswered questions.

Exercise types, intensity levels, and durations which most effectively increase these lymphatic and vascular benefits are still unknown. This effects can vary from person to person, so careful testing will be important when combining exercise with medical treatments.

Regular exercise does much more than just burn calories; it may actually help your body renew itself from the inside out. However, more research is required to turn this insight into useful anti-aging therapies.

Scientific References

  • 1. Gunin AG, Petrov VV, Golubtzova NN, Vasilieva OV, Kornilova NK. Age-related changes in angiogenesis in human dermis. Exp Gerontol 2014;55:143–151.
  • 2. Jiang, Jizong1,2; Zheng, Yongjun3; Wang, Rui1,2; Yang, Hao1,2; Zang, Shihui1,2; Chatterjee, Emeli4; Li, Guoping4,5; Cretoiu, Dragos6,7; Zhao, Cuimei8; Xiao, Junjie1,2. Exercise-induced angiogenesis and lymphangiogenesis: A potential therapeutic tool to fight aging and disease. Chinese Medical Journal 138(20):p 2552-2587, October 20, 2025.

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About the authors

Amy Peck - Expert Contributor

Amy Peck

Expert Contributor

Teddy Gordon - Editor-in-Chief

Teddy Gordon

Editor-in-Chief

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