Download #1 peptide tracker for GLP-1, weight loss & muscle gain with 50% OFF! #1 peptide tracker50% OFF! Download now

Hypoxic training does not outperform normal training in improving cardiometabolic health

Amy Peck - Expert Contributor
Contributed by Amy Peck Expert Contributor
Teddy Gordon - Editor-in-Chief
Written by Teddy Gordon Editor-in-Chief
Fact checked
Training 2 min read
Updated: Nov 22, 2025
Fact checked

Key Findings

  • Compared to normoxic (normal oxygen) training, hypoxic (low oxygen) training did not significantly improve insulin or fasting glucose levels in overweight or obese adults;
  • Blood pressure and the lipid profile were not considerably improved by hypoxic or normoxic training;
  • A small number of studies and variations in research protocols limit confidence in the additional benefit of hypoxia yet.

Recent meta-analysis revealed that overweight or obese adults, exercising in low oxygen (hypoxic) conditions, do not get any additional cardiometabolic benefits compared to training in a normal oxygen (normoxic) environment.

In an analysis of 9 randomized controlled trials, with overall 278 (about 45 years old)  overweight or obese participants, researchers compared the impact of low-oxygen and normal-oxygen exercises on blood pressure, lipids, and fasting glucose. [1]

Why It Matters

As a result, they found no differences in these activities. Training at high altitudes, using specialized equipment to reduce oxygen levels (like masks), or performing breath-holding exercises while training will probably not effect any cardiomethabolic benefits in obese people. 

It was noted that there is currently little proof to support the claim that hypoxic training gives a further advantage, despite the fact that it might be safe and may provide identical cardiometabolic benefits to traditional training. 

What to Keep in Mind

To find out whether specific conditions or populations might benefit more, they point out the need for larger, better-designed trials with uniform participant groups and standardized hypoxia protocols.

Larger studies with uniform protocols are needed to find out clear details and conditions related to hypoxic training for obese people.

Note, the majority of previous research used "relative hypoxia," which balances exercise intensity between hypoxic and normal oxygen, as opposed to "absolute hypoxia," which lowers oxygen but keeps the same load.

Bottom Line

You most likely won't gain more from low-oxygen training than from normal-oxygen training if you're an adult who is overweight or obese and exercising to improve metabolic health. Regular exercise is still extremely important.

Scientific References

  • 1. Gatti A, Cavallo C, Giuriato M, et al. Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta-analysis. Diabetes Obes Metab. 2025;

Why trust Longeviters.com

We have strict editorial guidelines. Every review, guide, or a new hack we share goes through a clear set of standards to ensure accuracy & fairness.
Our biohacking experts have analyzed & tested 150+ longevity tools, trends, and wellness products.
Longeviters recommendations & verdicts are not influenced by third-parties and are based on our own experience, findings and expertise.

About the authors

Amy Peck - Expert Contributor

Amy Peck

Expert Contributor

Teddy Gordon - Editor-in-Chief

Teddy Gordon

Editor-in-Chief

TOP 3 Most Popular Coupon Codes

Verified
Nurecover Independence Day Sale
Rating 5.0
Verified
Nordic Wave Memorial Day Sale
Rating 5.0
HigherDose Memorial Day Sale
Rating 5.0
×
50% OFF
Nurecover Independence Day Sale
0 DAYS
00 HOURS
00 MINUTES
00 SECONDS
GET DEAL